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Behavioral Nudges for Diabetes Prevention (BEGIN) Trial in Primary Care
Sponsor: Northwestern University
Summary
A large body of research has demonstrated that intensive lifestyle interventions and metformin are effective treatments to prevent or delay diabetes among high-risk adults, yet neither treatment is routinely used in practice. The Behavioral Nudges for Diabetes Prevention (BEGIN) Trial will test two low-touch interventions designed to motivate adoption of these treatments to prevent diabetes. Given that 38% of U.S. adults have prediabetes, the proposed study has potential for large public health impact by testing pragmatic, scalable, and sustainable approaches based in primary care to promote evidence-based treatment for this common condition.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
960
Start Date
2022-03-21
Completion Date
2026-09-01
Last Updated
2025-11-04
Healthy Volunteers
Yes
Conditions
Interventions
Decision Aid intervention
* Displays information about the benefits and risks of ILI and metformin * Asks open-ended questions: "What am I willing to do to prevent T2D?" and "What do I need to prevent T2D?" * Prompts patients to commit to immediate next steps * Health educator schedules interested patients for first ILI session or sends message to provider about patients' interest in starting metformin, if chosen
Text Messaging intervention
* Defines prediabetes and includes individualized A1c values * Present benefits and risks of intensive lifestyle intervention and metformin * States that other prediabetic Erie patients are adopting intensive lifestyle intervention and metformin * Encourages initiating intensive lifestyle intervention or discussing metformin with provider * Include selected behavioral content from diabetes prevention program * Initial message with automatic opt-in, allows opt-out for messages * Subsequent messages include: information about T2D risk and treatments; prompts to directly schedule intensive lifestyle intervention or office visit to discuss metformin; selected behavioral content from diabetes prevention programming
Usual Care
Patients receiving care at non-intervention clinic sites will not be exposed to treatment intervention.
Locations (1)
Northwestern University
Chicago, Illinois, United States