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Complete Mesocolic Excision in Comparison With Conventional Surgery for the Right Colon Cancer
Sponsor: University of Turin, Italy
Summary
An Italian randomized controlled trial parallel-group in patients with a malignant tumor of the right or proximal transverse colon requiring right hemicolectomy.
Official title: Complete Mesocolic Excision With Central Vascular Ligation in Comparison With Conventional Surgery for the Right Colon Cancer: An Italian Randomized Trial
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
416
Start Date
2020-07-13
Completion Date
2027-01-01
Last Updated
2022-11-14
Healthy Volunteers
No
Conditions
Interventions
Conventional Right hemicolectomy (Non-CME)
Transecting the Ileocolic Vein and Artery close to the Superior Mesenteric Vessels without clearing the superior mesenteric vein (SMV) from the adipose tissue. Transecting the Right Colic Vein and Artery and superior right colic vein (when present) peripherally. Transecting the Right branches of the Middle Colic Vein (MCV) and the Middle Colic Artery (MCA) peripherally, without clearing the main trunk of the MCV and the MCA. The Right Gastroepiploic Vein and artery are never transacted.
Right hemicolectomy with CME+CVL
Separation of the visceral fascia from the parietal fascia by sharp dissection leaving intact mesocolon coverage. Transecting the supplying vessels at their origin from the main vessels, particularly: * The Ileocolic Vessels, The Right Colic Vessels,The superior right colic vein (when present), The Right branches of the Middle Colic Vein and of the Middle Colic Artery * The MCV and MCA at their origin in case of cancer of the hepatic flexure or of the proximal third of the transverse colon, as well as The Right Gastroepiploic Vessels at their origin from the gastrocolic trunk of Henle (GCTH) and the gastroduodenal artery. The SMV should be cleared from all adipose tissue all along its anterior surface until its intrapancreatic entrance.
Locations (14)
Ospedale della Misericordia
Grosseto, Arezzo, Italy
Ospedale Città di Sesto San Giovanni
Sesto San Giovanni, Milano, Italy
S. Andrea Hospital
La Spezia, Spezia, Italy
Candiolo Cancer Institute - IRCCS
Candiolo, Torino, Italy
Ospedale E. Agnelli Pinerolo
Pinerolo, Torino, Italy
Maggiore Bellaria Hospital, Bologna
Bologna, Italy
Università degli Studi di Ferrara
Ferrara, Italy
Ospedale Policlinico San Martino
Genova, Italy
Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Messina, Italy
European Institute of Oncology
Milan, Italy
Federico II University
Naples, Italy
University of Rome Tor Vergata
Rome, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Rome, Italy
University of Turin (AOU.San Luigi Gonzaga)
Torino, Italy