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Neural Correlates of Real World Spatial Navigation in Humans
Sponsor: Duke University
Summary
The purpose of this study is to understand the neural mechanisms that support real world spatial navigation in humans using deep brain recordings and stimulation during virtual reality (VR), augmented reality, and real world memory tasks. We will determine the cognitive (i.e., memory) and behavioral (i.e., body, head, eye position and movement) factors that modulate deep brain activity and the consequent effects of memory-enhancing deep brain stimulation.
Key Details
Gender
All
Age Range
12 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2020-09-30
Completion Date
2026-06-30
Last Updated
2026-05-15
Healthy Volunteers
Yes
Conditions
Interventions
Deep Brain Stimulation
Deep brain stimulation will be used
Memory and spatial navigation tasks
Tasks may include walking around the room, on a treadmill, or in a controlled environment using VR (virtual reality) or AR (augmented reality) technology designed to simulate real-world navigation. Participants may also use Meta Ray-Ban glasses to capture new memories while recording neural activity.
Physiological Signals
Physiological signals such as heart rate, respiration, and skin conductance will be monitored while completing lab tasks. Motion capture and eye-tracking may also be used.
Questionnaires and Assessments
Participants complete questionnaires and assessments to assess subjective emotional experience.
Locations (2)
University of California, Los Angeles
Los Angeles, California, United States
Duke University
Durham, North Carolina, United States