Clinical Research Directory

Inclusion Criteria: "Case" Patient : * with nephronophthisis or ciliopathy with known genetic diagnosis or not * signed the Informed consent form (patient or legal guardians if minor/incapable major) * no limit of age, this patients could be recruited from the birth * social insurance affiliation Healthy related individual : * related with a included patient (father, mother, brother, sister) * signed the Informed consent form (major or legal guardians if minor/incapable major) * no limit of age, this patients could be recruited from the birth * social insurance affiliation "Negative Control" patient : * without chronic renal failure * signed the Informed consent form (major or legal guardians if minor/incapable major) * no limit of age, this patients could be recruited from the birth * social insurance affiliation "Positive Control" patient : * with chronic renal failure not related with a ciliary dysfunction * signed the Informed consent form (major or legal guardians if minor/incapable major) * no limit of age, this patients could be recruited from the birth * social insurance affiliation Exclusion Criteria "Case" Patient : * pregnant, parturious and nursing mothers. * with functional renal graft * use an experimental treatment during 30 days before inclusion date Healthy related individual : \- pregnant, parturious and nursing mothers. "Negative Control" patient : \- pregnant, parturious and nursing mothers. "Positive Control" patient : * pregnant, parturious and nursing mothers. * with functional renal graft * use an experimental treatment during 30 days before inclusion date