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Phenotype, Genotype and Biomarkers 2
Sponsor: University of Miami
Summary
The purpose of this study is to learn more about amyotrophic lateral sclerosis (ALS) and other related neurodegenerative diseases, including frontotemporal dementia (FTD), primary lateral sclerosis (PLS), hereditary spastic paraplegia (HSP), progressive muscular atrophy (PMA) and multisystem proteinopathy (MSP). More precisely, the investigator wants to identify the links that exist between the disease phenotype (phenotype refers to observable signs and symptoms) and the disease genotype (genotype refers to your genetic information). The investigator also wants to identify biomarkers of ALS and related diseases.
Key Details
Gender
All
Age Range
7 Years - Any
Study Type
OBSERVATIONAL
Enrollment
217
Start Date
2021-01-08
Completion Date
2028-08
Last Updated
2026-03-23
Healthy Volunteers
Yes
Conditions
Locations (4)
University of Miami
Miami, Florida, United States
University of Kansas Medical Center
Kansas City, Kansas, United States
University of Pennsylvania
Philadelphia, Pennsylvania, United States
University of Cape Town
Cape Town, South Africa