Clinical Research Directory

Inclusion Criteria: * Histologically confirmed local recurrence of breast cancer after close resection (≤1mm Resection margin), R1 or R2 resection respectively inoperable recurrence of the chest wall * age ≥18 Jahre * ECOG PS 0-2 * Estimated life expectancy more than 2 years * Informed consent Exclusion Criteria: * Extensive distant metastases that have an estimated life expectancy of \<2a * Heart disease: severe heart failure (NHYA III / IV), coronary heart disease, state after Myocardial infarction within the last 6 months), AV block III ° * Cardiac pacemaker * Second malignancy (except cervical carcinomas in situ, local controlled basaliomas, superficial bladder carcinomas (Ta, Tis, T1) or other carcinomas that have lasted more than 5 years behind and have been treated curatively) * Pregnancy or breastfeeding * Implanted port on the side to be treated in the Hyperthermia field (located contralateral is not an exclusion criteria) * Subclavian vein thrombosis less than \<6 months behind * Other circumstances that preclude hyperthermia * Circumstances that conflict with regular follow-up care * Transplanted organs * Other implants of the ipsilateral chest wall