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ACTIVE NOT RECRUITING
NCT04882254
PHASE2

Normothermic Machine Perfusion: an Additional Value for Kidney Transplant Outcomes?

Sponsor: Erasmus Medical Center

View on ClinicalTrials.gov

Summary

This study is a randomised, controlled, phase II trial to assess the efficacy of 2 hours normothermic machine perfusion (NMP) of extended criteria(EC)-DBD (donation after brain death) and DCD (donation after circulatory death) donor kidneys compared to standard care, which is hypothermic machine perfusion (HMP) only in the Netherlands.

Official title: Normothermic Machine Perfusion as Additional Value to Hypothermic Machine Perfusion for Kidney Transplant Outcomes. A Single-centre, Open-label, Randomised, Controlled Trial.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

80

Start Date

2021-05-01

Completion Date

2025-05

Last Updated

2024-05-07

Healthy Volunteers

No

Interventions

PROCEDURE

Normothermic machine perfusion

Additional 2h of normothermic machine perfusion of the donor kidney with a red cell based perfusate.

Locations (1)

Erasmus MC Transplant Institute

Rotterdam, Netherlands