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TERMINATED
NCT04882943

COllaboration REsearch on Chronic Cough (COREC): a French Multicenter Database

Sponsor: University Hospital, Toulouse

View on ClinicalTrials.gov

Summary

Chronic cough (TC), defined by a duration exceeding 8 weeks, is a particularly frequent symptom with a prevalence observed at 9.6% 1. Chronic cough is the cause of a major handicap for patients with a impact on their quality of life 2. Although CT is common, management is often delicate and complex. In studies, asthma, gastroesophageal reflux disease, posterior flushing, rhino-sinusitis, or taking tussigenic medications are common causes of chronic coughs. However, chronic refractory or unexplained cough, which corresponds to cough for which no cause has been found or the treatments directed against the cause of the cough have not made it possible to resolve the cough, is a real problem in practice. nick3. There is currently no prospective data in France on the characteristics of chronic cough (etiologies, response to treatment) and the percentage of refractory cough. The aim of the study is to constitute a French prospective multicenter hospital cohort of chronic cough patients in order to identify, for the first time in France in a prospective and multicenter manner, the frequency of patients with refractory cough among chronic cough patients.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

178

Start Date

2021-06-22

Completion Date

2026-04-02

Last Updated

2026-04-14

Healthy Volunteers

No

Interventions

OTHER

questionnaires

Quality of life questionnaires

Locations (6)

CHU de Besançon

Besançon, France

CHU de Bordeaux

Bordeaux, France

CH de Libourne

Libourne, France

AP-HP Bichat

Paris, France

UHToulouse

Toulouse, France

CHU de Tours

Tours, France