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Predictors of Disease Severity in COVID-19 Patients
Sponsor: Zeljko Mijailovic
Summary
The primary goal of the VIRIONUM project is to analyze the association of clinical, socio-demographic characteristics of patients and their genetic polymorphism, inflammatory and other biochemical markers with disease progression and death in subjects with COVID-19 disease. The research is an observational, cohort study with nested-case control design, including adult, male and female COVID-19 inpatients. Primary dependent variable will be outcome of disease, defined as discharge from the hospital or death. The outcomes and putative risk factors will be analyzed using binary logistic regressions. The proposed multi- and inter-disciplinary study should provide additional scientific evidence about risk factors for the development of severe forms of the disease and the COVID-19-related death.
Official title: Biochemical, Inflammatory and Genetic Factors in Patients With COVID-19
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
818
Start Date
2020-04-04
Completion Date
2024-02-29
Last Updated
2026-04-28
Healthy Volunteers
No
Conditions
Interventions
Standard of health care
The patients in this observational study will be exposed to the standard health care interventions according to the hospital diagnostic and treatment protocols and procedures and clinical judgment of the treating physicians.
Locations (5)
Spitali Amerikan
Tirana, Albania
General Hospital "Prim. dr. Abdulah Nakaš"
Sarajevo, Bosnia and Herzegovina
KBC Rijeka, University of Rijeka
Rijeka, Croatia
University of Montenegro, Faculty of Medicine
Podgorica, Montenegro
Faculty of Medical Sciences, University Clinical Center Kragujevac
Kragujevac, Srbija, Serbia