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COMPLETED
NCT04888169
NA

Studying the Modification of Attention Bias Remotely After Trauma

Sponsor: University of California, San Francisco

View on ClinicalTrials.gov

Summary

The investigators will complete an entirely remote randomized controlled trial (RCT) comparing 14 sessions of attention bias modification (ABM), attention control training (ACT), placebo neutral attention training, and a final control condition with daily questions in 1,897 individuals with clinically significant Post-traumatic Stress Symptoms (PTSS) (defined as PCL-5 score ≥ 33). To assess effects of the training and control conditions, the investigators will administer tests of threat-related attention bias and variability, and self-report assessments of PTSS, depression, anxiety, and perceived stress at baseline, after one and two weeks of training, and at eight-week follow up. The investigators plan to screen and confirm interest from over 3,000 eligible participants over a period of 24 months to enroll and randomize 1,897 participants with the end goal of 1,232 completers (176 per condition).

Official title: Optimizing Attention Bias Modification for Posttraumatic Stress Disorder: An Entirely Remote Study

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

1314

Start Date

2023-04-20

Completion Date

2025-06-30

Last Updated

2026-07-23

Healthy Volunteers

No

Interventions

DEVICE

SMART Mobile App - Attention Bias Modification

ABM involves placing the probe behind the neutral stimulus on 100% of the trials.

DEVICE

SMART Mobile App - Attention Control Training

ACT involves placing the probe behind the neutral stimulus on 50% of trials, and behind the threat stimulus on 50% of trials.

DEVICE

SMART Mobile App - Placebo Training

Placebo training only includes neutral stimuli.

DEVICE

SMART Mobile App - Control

Participants will only answer questions.

Locations (1)

Tommy Atwater

San Francisco, California, United States