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Studying the Modification of Attention Bias Remotely After Trauma
Sponsor: University of California, San Francisco
Summary
The investigators will complete an entirely remote randomized controlled trial (RCT) comparing 14 sessions of attention bias modification (ABM), attention control training (ACT), placebo neutral attention training, and a final control condition with daily questions in 1,897 individuals with clinically significant Post-traumatic Stress Symptoms (PTSS) (defined as PCL-5 score ≥ 33). To assess effects of the training and control conditions, the investigators will administer tests of threat-related attention bias and variability, and self-report assessments of PTSS, depression, anxiety, and perceived stress at baseline, after one and two weeks of training, and at eight-week follow up. The investigators plan to screen and confirm interest from over 3,000 eligible participants over a period of 24 months to enroll and randomize 1,897 participants with the end goal of 1,232 completers (176 per condition).
Official title: Optimizing Attention Bias Modification for Posttraumatic Stress Disorder: An Entirely Remote Study
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
1314
Start Date
2023-04-20
Completion Date
2025-06-30
Last Updated
2026-07-23
Healthy Volunteers
No
Conditions
Interventions
SMART Mobile App - Attention Bias Modification
ABM involves placing the probe behind the neutral stimulus on 100% of the trials.
SMART Mobile App - Attention Control Training
ACT involves placing the probe behind the neutral stimulus on 50% of trials, and behind the threat stimulus on 50% of trials.
SMART Mobile App - Placebo Training
Placebo training only includes neutral stimuli.
SMART Mobile App - Control
Participants will only answer questions.
Locations (1)
Tommy Atwater
San Francisco, California, United States