Clinical Research Directory

Inclusion Criteria: * Age \>18 years * Women that had a laparotomy no more than 3 weeks before accrual. * Surgical wound dehiscence that requires a secondary closure. * Time from wound dehiscence \>24 hours and \<6 days. * The open wound includes epidermis, dermis and sub cutaneous fat. * The patient can sign an informed consent form. Exclusion Criteria: * Patients with necrotizing fasciitis * Patients with fascial dehiscence * Cannot withdraw blood in the required amount (up to 18 mL per week). * Known coagulation problems, abnormal thrombocytes level or if heparin is given intravenously. Subjects who are taking oral anti-coagulants or anti-agreganrts will not be excluded. * Pregnancy * Subject is currently receiving (i.e., within the past 30 days) or scheduled to receive systemic steroids (Prednisone- more than 10mg/d or equivalent).