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Study of Dextromethorphan in OCD and Related Disorders
Sponsor: Stanford University
Summary
The purpose of the study is to assess the tolerability and efficacy of dextromethorphan in combination with fluoxetine for symptom relief in OCD and related disorders.
Official title: Fluoxetine/Dextromethorphan in Obsessive-Compulsive and Related Disorders: an Open-Label Crossover Pilot Study
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2022-01-20
Completion Date
2026-12-01
Last Updated
2025-08-27
Healthy Volunteers
No
Conditions
Interventions
Fluoxetine
Fluoxetine 20mg (or previously prescribed dose) will be taken once daily by mouth for 8 weeks
Dextromethorphan
Dextromethorphan, an over-the-counter cough suppressant, will be taken by mouth twice daily for four weeks of the study, starting at 15mg per dose, and increasing weekly as tolerated to a maximum of 60mg per dose.
Locations (1)
Stanford University
Stanford, California, United States