Clinical Research Directory

Inclusion Criteria: 1. Diagnose MS according to revised McDonald criteria 2. Give written informed consent. 3. Have an age between 18-70 years. 4. Have stable disease without attack or progression of loss of function in the last three months. 5. Have self-reported spasticity, scored using the numeric rating scale (NRS) which describes the average score of spasticity over the last 24 hours, at ≥ 4 (where the scale scores spasticity from 0-10, where 0 is no spasticity, and 10 is worst possible spasticity), - combined with pain in the lower extremities last 24 hours 6. Have tried standard treatment for spasticity and pain without achieving a satisfactory effect. 7. Stable and unchanged treatment of spasticity and pain the last month 8. Stable and unchanged disease-modulating treatment for MS last 6 months. 9. Function level measured by the Expanded Disability Status Scale (EDSS) 2.0-6.5 10. Can self-manage study equipment. Exclusion Criteria: 1. Have spasticity due to a disease other than MS. 2. Pregnancy or plan a pregnancy within the upcoming study period of 6 months. 3. Have an ongoing infection. 4. Have received botulinum toxin injection for spasticity within the last 4 months. 5. Have symptoms or illness that make it difficult to participate in the study. 6. Having planned surgery or other treatment within the coming study period of 6 months makes it difficult to participate in the study. 7. Have functional scores outside inclusion criteria measured by EDSS 2.0-6.5 8. Have had disease activity beyond requirements for stable disease as described in inclusion criteria 9. Have changed drug treatment beyond requirements for stable treatment as described in inclusion criteria.