Clinical Research Directory

Inclusion Criteria: * Age ≥ 18 years. * Chest pain or other complaints suspect of ACS for at least 2 hours where the GP or emergency medical personnel are in need of further diagnostics or risk stratification to come to a decision of referral. * Patients, who have been informed of the nature of the study, agree to its provisions and have provided written informed consent. Exclusion Criteria: * Electrocardiographic ST-segment elevation/High suspicion of STE-ACS. * Suspicion of an acute non-coronary diagnosis e.g. pulmonary embolism, thoracic aortic dissection or other life-threatening disease. * Patients presenting cardiogenic shock, defined as: systolic blood pressure \<90mmHg and heart rate \>100 and peripheral oxygen saturation \<90% (without oxygen administration) * Patients presenting with sudden onset heart rhythm disorders and second or third degree atrioventricular block. * Patients with confirmed ACS, PCI or CABG \<30 days prior to inclusion. * Impaired consciousness defined as an EMV \<8. * Severe shortness of breath. * Patients with known end-stage renal disease (dialysis and/or MDRD \< 30 ml/min). * Patients with known cognitive impairment. * Communication issues with patient/language barrier. * Patients already participating in an interventional cardiology or cardiovascular trial.