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Early Tranexamic Acid and Modulating the Inflammatory Response in Sepsis
Sponsor: Assiut University
Summary
In this study, our aim is to investigate the role tranexamic acid in modulating inflammation in patients with sepsis.
Official title: Could Early Tranexamic Acid Safely Serve as an Anti-inflammatory Treatment for Patients With Sepsis? A Randomized Double Blind Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2021-06-05
Completion Date
2027-01-30
Last Updated
2025-08-05
Healthy Volunteers
No
Conditions
Interventions
Tranexamic acid
administer 1 gram of TXA in 100 ml of 0.9% normal saline, intravenous over 10 minutes as soon as possible but no later than three hours after diagnosis, infuse a second gram of TXA IV over 8 hours in 0.9% normal saline for first 3 days.
0.9% saline
administer the same volume (100ml normal saline) and same duration (first three days).
Locations (1)
Assiut university hospital
Asyut, Egypt