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ACTIVE NOT RECRUITING
NCT04911478

Long-term Follow-up Study of Allogeneic Gamma Delta (γδ) CAR T Cells

Sponsor: Adicet Therapeutics

View on ClinicalTrials.gov

Summary

The purpose of this study is to assess long-term side effects from subjects who receive an Adicet Bio γδ CAR T cell product. Subjects will join this study once they complete the parent interventional study. No additional study drug will be given, but subjects can receive other therapies for their cancer while they are being followed for long term safety in this study. For a period of 15 years from the first administration of Adicet Bio allogeneic γδ CAR T cell product, subjects will be assessed for long-term safety and survival through collection of data that include safety, efficacy, pharmacokinetics and immunogenicity.

Official title: Long-term Follow-up Protocol for Subjects Treated With Adicet Allogeneic Gamma Delta (γδ) CAR T Cell Investigational Products

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

50

Start Date

2022-02-14

Completion Date

2039-08

Last Updated

2026-04-09

Healthy Volunteers

No

Interventions

GENETIC

ADI-001

No study drug is administered in this study. Patients who have received Adicet allogeneic γδ CAR T cell therapy will be evaluated in this trial for long-term safety and efficacy

Locations (5)

Blood and Marrow Transplant Program

Palo Alto, California, United States

Norton Cancer Institute

Louisville, Kentucky, United States

Baylor Scott & White Research Institute

Dallas, Texas, United States

MD Anderson Caner Center

Houston, Texas, United States

Medical College of Wisconsin

Milwaukee, Wisconsin, United States