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Factors Influencing the Prognosis of Olfactory Dysfunction After Upper Sensation
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
Summary
Objective: This study aimed to analyze the outcomes of post-infectious olfactory dysfunction treated with different doses of corticosteroids and specify factors related to the curative effect. Methods: The medical records of patients diagnosed with post-infectious olfactory dysfunction from January 2020 to december 2025 were reviewed. All patients were treated with different doses of oral corticosteroids for 12 days or they inhaled corticosteroids for 1 month.
Official title: Second Affiliated Hospital, College of Medicine, Zhejiang University
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2021-06-02
Completion Date
2026-12-30
Last Updated
2021-06-09
Healthy Volunteers
No
Conditions
Interventions
methylprednisolone
The patients were treated with three protocols: (1) oral methylprednisolone, 40 mg for 3 days, 20 mg for 3 days, and 8 mg for 6 days; (2) oral methylprednisolone, 20 mg for 3 days, 10 mg for 3 days, and 4 mg for 6 days. At the same time, all patients received olfactory training for 12 weeks as proposed by Hummel et al
budesonide atomization suspension
(3) budesonide atomization suspension (AstraZeneca Trading Co., Ltd, AU.) inhaled through the nose atomized with an air compression atomizer for 4 weeks, 2 mg for the first 2 weeks and reduced to 1 mg for the last 2 weeks. At the same time, all patients received olfactory training for 12 weeks as proposed by Hummel et al
Locations (1)
Department of Otolaryngology, Second Affiliated Hospital, College of Medicine, Zhejiang University
Hangzhou, Zhejiang, China