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RECRUITING
NCT04920318
NA

Enhancing Language Function in Primary Progressive Aphasia

Sponsor: University of Arizona

View on ClinicalTrials.gov

Summary

This study's goal is to use non-invasive brain stimulation (NBS) techniques to treat language impairment associated with Primary Progressive Aphasia (PPA). The purpose of this study is to combine behavioral language intervention with individualized noninvasive brain stimulation techniques, called transcranial direct current stimulation (tDCS) to help the brain reorganize around damage and improve language functions.

Official title: Enhancing Language Function in Primary Progressive Aphasia (PPA) With Transcranial Direct Current Stimulation (tDCS)

Key Details

Gender

All

Age Range

45 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2021-08-30

Completion Date

2027-06-15

Last Updated

2024-11-29

Healthy Volunteers

No

Interventions

COMBINATION_PRODUCT

tDCS + language therapy

In this study fMRI-guided noninvasive neuromodulation will be applied, called Transcranial Direct Current Stimulation (tDCS) to the frontal and parietal brain regions that show reduced activation but still are structurally intact. TDCS will be paired with personalized speech-language therapy to enhance language functions.

COMBINATION_PRODUCT

sham TDCS + language therapy

sham control will be applied with language therapy to the same regions as active TDCS.

Locations (1)

University of Arizona

Tucson, Arizona, United States