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Enhancing Language Function in Primary Progressive Aphasia
Sponsor: University of Arizona
Summary
This study's goal is to use non-invasive brain stimulation (NBS) techniques to treat language impairment associated with Primary Progressive Aphasia (PPA). The purpose of this study is to combine behavioral language intervention with individualized noninvasive brain stimulation techniques, called transcranial direct current stimulation (tDCS) to help the brain reorganize around damage and improve language functions.
Official title: Enhancing Language Function in Primary Progressive Aphasia (PPA) With Transcranial Direct Current Stimulation (tDCS)
Key Details
Gender
All
Age Range
45 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2021-08-30
Completion Date
2027-06-15
Last Updated
2024-11-29
Healthy Volunteers
No
Conditions
Interventions
tDCS + language therapy
In this study fMRI-guided noninvasive neuromodulation will be applied, called Transcranial Direct Current Stimulation (tDCS) to the frontal and parietal brain regions that show reduced activation but still are structurally intact. TDCS will be paired with personalized speech-language therapy to enhance language functions.
sham TDCS + language therapy
sham control will be applied with language therapy to the same regions as active TDCS.
Locations (1)
University of Arizona
Tucson, Arizona, United States