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AVAILABLE
NCT04921956

Compassionate Use of Concizumab if You Have Haemophilia

Sponsor: Novo Nordisk A/S

View on ClinicalTrials.gov

Summary

The compassionate use programme will give participants concizumab for free, even though it is not yet approved by health authorities. This is because participants need this medicine to treat their haemophilia properly. The programme will check that participants are safe and that the medicine works for them. The programme may last for years. Participants will take one injection under their skin every day. Participants will have 4-5 visits with the study doctor for the first half year. After that they will have 1 visit every half year. At all clinic visits participants will have blood samples taken. Participants will fill in a diary between the visits. A patient is considered to have completed the programme when any of the following criteria occurred first: 1) when the patient is included in a clinical trial with concizumab or 2) up to 6 months after concizumab is commercially available in the patient's country and approved for the patient (The time span of 6 months should provide ample time for the patient to obtain concizumab commercially) or 3) the sponsor decides to discontinue concizumab clinical development for the patient's population.

Official title: Concizumab Compassionate Use Programme for Patients With Congenital Haemophilia

Key Details

Gender

All

Age Range

Any - Any

Study Type

EXPANDED_ACCESS

Enrollment

Not specified

Start Date

Not specified

Completion Date

Not specified

Last Updated

2026-09-10

Healthy Volunteers

No

Interventions

DRUG

Concizumab

Injected under the skin (subcutaneous, sc) once daily, individual dose adjustment.

Locations (25)

Children's Hospital Los Angeles - Endocrinology

Los Angeles, California, United States

University of California San Francisco UCSF

San Francisco, California, United States

Connecticut Children's Medical Center

Hartford, Connecticut, United States

Georgetown University Medical Center

Washington D.C., District of Columbia, United States

Augusta University

Augusta, Georgia, United States

Memorial Health University Medical Center

Savannah, Georgia, United States

St. Luke's Mountain States Tumor Institute

Boise, Idaho, United States

Childrens Hospital of Chicago

Chicago, Illinois, United States

Indiana Hemophilia-Thromb Ctr

Indianapolis, Indiana, United States

Children's Hosp-New Orleans

New Orleans, Louisiana, United States

Children's Hospital of Michigan

Detroit, Michigan, United States

Southern Specialty Clinic

Flowood, Mississippi, United States

Louisiana Ctr for Adv Med-LCAM

Madison, Mississippi, United States

The Children's Mercy Hospital

Kansas City, Missouri, United States

Children's Nebraska

Omaha, Nebraska, United States

ECU Sickle Cell Comp Clinic

Greenville, North Carolina, United States

Nationwide Children's Hospital

Columbus, Ohio, United States

Penn State Hershey Medical Center

Hershey, Pennsylvania, United States

BI-LO Chrt Childn's Cancer Ctr

Greenville, South Carolina, United States

Cook Children's Hospital-Hematology-Oncology

Fort Worth, Texas, United States

Texas Children's Hospital_Houston

Houston, Texas, United States

Univ TX Hlth Sci Ctr Houston

Houston, Texas, United States

Virginia Cwealth Univ Richmond

Richmond, Virginia, United States

UMHAT Sveti Georgi EAD, Plovdiv, Clinic of Pediatrics

Plovdiv, Bulgaria

Koagulationsmottagningen

Solna, Sweden