Clinical Research Directory
Browse clinical research sites, groups, and studies.
Therapeutic Effect of New Biologics in Crohn's Disease
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University
Summary
New types of biologics have brought advantages in therapy strategies for Crohn's disease. However, clinical data evaluating their efficacy and adverse in China is lacking. We aimed to evaluate the short-term and long-term therapeutic effect as well as drug adverse of Ustekinumab (UST) and Vedolizumab (VED). Besides, we aim to figure out the independent factors predicting the effectiveness of new biologics. Relations between drug exposure (trough concentration and antibody concentration) and therapeutic efficacy are study in-depth by this retrospective observational study.
Key Details
Gender
All
Age Range
17 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2021-06-10
Completion Date
2025-03-29
Last Updated
2026-04-27
Healthy Volunteers
No
Locations (1)
the Sixth Affiliated Hospital of Sun Yat-Sen University
Guangzhou, Guangdong, China