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ACTIVE NOT RECRUITING
NCT04924985
NA

Goal-directed CPR Using Cerebral Oximetry

Sponsor: NYU Langone Health

View on ClinicalTrials.gov

Summary

The proposed study is a single-center, randomized controlled pilot trial of adults who suffer in-hospital cardiac arrests. Using cerebral oxygenation and end-tidal carbon dioxide physiological targets to predict survival and neurological outcome, the impact of physiological-feedback CPR will be assessed. 150 adult patients who have a cardiac arrest event at NYU Tisch Hospital will be randomized to one of two treatment groups: (1) Physiological-Feedback CPR or (2) Non-Physiological (Audiovisual) Feedback CPR.

Official title: Goal-Directed Cardiopulmonary Resuscitation in Cardiac Arrest Using a Novel Physiological Target

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

150

Start Date

2022-02-11

Completion Date

2025-07-31

Last Updated

2025-03-27

Healthy Volunteers

No

Interventions

OTHER

Non-Physiological Feedback CPR

Non-physiologically guided CPR using AV feedback (integrated into defibrillators)

OTHER

Physiological Feedback CPR

Physiological feedback CPR using an optimal regional O2 Saturation (rSO2), End-tidal CO2 (ETCO2) or combined (rSO2/ETCO2) target

Locations (1)

NYU Langone Health

New York, New York, United States