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Goal-directed CPR Using Cerebral Oximetry
Sponsor: NYU Langone Health
Summary
The proposed study is a single-center, randomized controlled pilot trial of adults who suffer in-hospital cardiac arrests. Using cerebral oxygenation and end-tidal carbon dioxide physiological targets to predict survival and neurological outcome, the impact of physiological-feedback CPR will be assessed. 150 adult patients who have a cardiac arrest event at NYU Tisch Hospital will be randomized to one of two treatment groups: (1) Physiological-Feedback CPR or (2) Non-Physiological (Audiovisual) Feedback CPR.
Official title: Goal-Directed Cardiopulmonary Resuscitation in Cardiac Arrest Using a Novel Physiological Target
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2022-02-11
Completion Date
2025-07-31
Last Updated
2025-03-27
Healthy Volunteers
No
Conditions
Interventions
Non-Physiological Feedback CPR
Non-physiologically guided CPR using AV feedback (integrated into defibrillators)
Physiological Feedback CPR
Physiological feedback CPR using an optimal regional O2 Saturation (rSO2), End-tidal CO2 (ETCO2) or combined (rSO2/ETCO2) target
Locations (1)
NYU Langone Health
New York, New York, United States