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TERMINATED
NCT04926220

Dynamic Estimation of Cardiac Output in the Operating Room

Sponsor: Assistance Publique - Hôpitaux de Paris

View on ClinicalTrials.gov

Summary

During major surgery, it is recommended to monitor invasive arterial blood pressure and cardiac output (CO) during hemodynamic interventions (fluid challenge or vasopressors). Esophageal Doppler is currently considered as the reference method for monitoring cardiac output in the operating room. The PRAM method (pressure recording analytical method) with the MostCareUp monitor (Vytech, Padova, Italy) and the LTIA method (long time interval analysis) allow cardiac output estimation derived from non-calibrated arterial pressure waveform analysis. Few studies have looked at relative changes in cardiac output during hemodynamic intervention with these two methods. The aim of this study is to compare the relative changes in cardiac output during hemodynamic interventions as measured using PRAM and LTIA methods, compared to esophageal Doppler.

Official title: Estimation of Cardiac Output in the Operating Room by Pulse Wave Analysis and Esophageal Doppler Blood Velocity: Comparison of the Two Methods

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

36

Start Date

2021-09-15

Completion Date

2022-07-27

Last Updated

2026-09-22

Healthy Volunteers

No

Interventions

DEVICE

Trans-esophageal Doppler monitoring

Trans-esophageal Doppler monitoring (CARDIOQ-ODM; Deltex Medical, Chichester, UK) for monitoring of cardiac output

DEVICE

MostCareUP Haemodynamic Monitor

MostCareUp (Vytech, Padova, Italy) waveform analysis cardiac output monitor

DEVICE

Argos Cardiac Output (CO) Monitor

Argos monitor (Retia Medical, Valhalla, NY, USA) for cardiac output monitoring

Locations (1)

AP-HP, Lariboisière Hospital, Department of Anesthesiology and Intensive Care

Paris, France