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RECRUITING
NCT04942093
NA

NUTritional Impact of a Hypocaloric Hyperprotein Diet Before Obesity Surgery

Sponsor: University Hospital, Rouen

View on ClinicalTrials.gov

Summary

Obesity is a major public health problem and is constantly on the rise. Therapeutic approaches based on dietary advice, physical activity and the management of psychological difficulties are not always sufficient to achieve a lasting weight reduction. Bariatric surgery (or obesity surgery), accompanied by therapeutic education and adequate medical and dietary monitoring, can lead to significant and lasting weight loss. It is indicated as a second-line treatment for patients who have failed medical treatment, whose BMI is greater than or equal to 40 or whose BMI is greater than or equal to 35 with comorbidities (type 2 diabetes, arterial hypertension, obstructive sleep apnoea-hypopnoea syndrome, severe joint disorders). The surgeon may be very bothered by the intra-abdominal fat mass and especially by steatotic hepatomegaly (increase in the size of the liver and its fat load). Faced with this problem, various preoperative strategies such as the placement of an intra gastric balloon have been tried to decrease the size of the liver but a systematic review from 2016 indicates that a low calorie diet is preferable. Preoperative weight loss can reduce fat load and liver volume very rapidly. This meta-analysis shows that all low-calorie, high-protein diets are effective and that the optimal duration (4 weeks), compliance and tolerance are important factors for success.

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

200

Start Date

2023-10-09

Completion Date

2027-03-20

Last Updated

2025-09-22

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

With low-calorie, high-protein diet

A low-calorie, high-protein diet will be prescribed to the patient for a period of 4 weeks. The diet will be done the 4 weeks before the bariatric surgery

DIETARY_SUPPLEMENT

Without low-calorie, high-protein diet

A low-calorie, high-protein diet will not be prescribed to the patient for a period of 4 weeks.

Locations (3)

Ch Dieppe

Dieppe, France

HPE

Le Havre, France

CHU de ROUEN

Rouen, France