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ACTIVE NOT RECRUITING
NCT04946084
NA

Dynamic Change and Immune Response to Nasopharyngeal Carriage and Acute Otitis Media Pathogens

Sponsor: Rochester General Hospital

View on ClinicalTrials.gov

Summary

The investigators seek to conduct a prospective, longitudinal study to identify the dynamic changes in nasopharyngeal (NP) colonization patterns and acute otitis media (AOM) etiology involving antibiotic-resistant Streptococcus pneumoniae (Spn) and Haemophilus influenzae (Hflu).

Key Details

Gender

All

Age Range

6 Months - 36 Months

Study Type

INTERVENTIONAL

Enrollment

320

Start Date

2021-01-01

Completion Date

2026-12-31

Last Updated

2025-07-29

Healthy Volunteers

Yes

Interventions

PROCEDURE

Tympanocentesis

When acute otitis media is diagnosed, local anesthetic applied, small hole placed in eardrum, middle ear fluid extracted.

OTHER

Nasal Phalangeal Swab and Wash

Nasal phalangeal swab used to retrieve sample. Nasal wash used to retrieve sample.

OTHER

Blood Draw

Venipuncture

Locations (1)

Rochester General Hospital

Rochester, New York, United States