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COMPLETED
NCT04950153
NA

Intensive Combination Approach to Rollback the Epidemic in Nigerian Adolescents: UH3 Phase

Sponsor: Northwestern University

View on ClinicalTrials.gov

Summary

Combination interventions with mHealth and Peer Navigation components will be evaluated in a randomized, stepped wedge trial among youth in Ibadan, Lagos, Sagamu, and Jos, Nigeria. Study findings will demonstrate whether or not the combination interventions for HIV treatment outcomes, which were found to be efficacious in our prior pilot UG3 trial, will remain efficacious if scaled as proposed in this UH3 trial, across multiple sites.

Key Details

Gender

All

Age Range

15 Years - 24 Years

Study Type

INTERVENTIONAL

Enrollment

541

Start Date

2021-04-15

Completion Date

2024-12-31

Last Updated

2026-04-21

Healthy Volunteers

Yes

Interventions

BEHAVIORAL

Peer navigation

Peer navigators will navigate youth with HIV to provide assistance and support to optimize adherence to antiretroviral treatment (ART)

BEHAVIORAL

SMS Text messaging

Short Message System (SMS) text messages to remind and encourage youth to adhere to their ART

Locations (6)

University of Ibadan

Ibadan, Nigeria

Jos University Teaching Hospital

Jos, Nigeria

Lagos State University Teaching Hospital

Lagos, Nigeria

Lagos University Teaching Hospital

Lagos, Nigeria

Nigerian Institute of Medical Research (NIMR)

Lagos, Nigeria

Olabisi Onabanjo University Teaching Hospital

Sagamu, Nigeria