Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
ACTIVE NOT RECRUITING
NCT04953715

Microbiome and Immunosuppression: The Mission Study

Sponsor: The University of Texas Medical Branch, Galveston

View on ClinicalTrials.gov

Summary

The purpose of this research is to study immunosuppression drugs, certain foods, and how they can change the microbiome (the natural microorganisms inside the body) of the individual taking the immunosuppressive medications. The study team wants to study how the microbiome affects how the body processes the transplant medication.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

140

Start Date

2020-02-12

Completion Date

2033-01-01

Last Updated

2025-06-15

Healthy Volunteers

No

Interventions

OTHER

collection of body microbiome

A prospective, observational microbiome study of adult kidney transplant recipients receiving mycophenolate mofetil and tacrolimus maintenance immunosuppression. Participants will be studied post-transplant for mycophenolate pharmacokinetics and microbiome samples collected. Clinically measured tacrolimus trough concentrations will also be evaluated. Associations among mycophenolic acid enterohepatic recycling and metabolite formation, tacrolimus troughs, immunosuppression adverse effects, diarrhea and microbiome will be studied.

Locations (2)

University of Minnesota

Minneapolis, Minnesota, United States

HCMC

Minneapolis, Minnesota, United States