Clinical Research Directory
Browse clinical research sites, groups, and studies.
Study of an Environmental Risk Factor in Crohn's Disease
Sponsor: University Hospital, Lille
Summary
Inflammatory bowel disease (IBD) are lifelong chronic diseases affecting the gastrointestinal tract. The precise etiology and the different actors participating to the pathophysiological process leading to the disease development are still not well understood. A complex interaction between genetics, gut microbiota and environmental factors is thought to trigger the inappropriate mucosal immune response observed in IBD patients. We hypothesize that DON might be an environmental risk factor for IBD.The focus on the human relevance of the gut effects of DON by studying its exposure, metabolism and adverse effects in health and disease focusing on IBD patients
Official title: dEoxyniValenol as Risk Factor for Inflammatory Bowel Diseases: Human detoxifiCaTion and Impact On intestiNal Microbiota and Homeostasis
Key Details
Gender
All
Age Range
25 Years - 60 Years
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2021-09-27
Completion Date
2026-07
Last Updated
2025-12-26
Healthy Volunteers
Yes
Conditions
Locations (1)
Lille University Hospital
Lille, France