Clinical Research Directory

Inclusion Criteria: * healthy subjects; * men and women; * age 18-65 years; * 25 kg/m2 ≤ BMI ≤ 35 kg/m2; * habitual daily pasta consumption (≥ 1 portion/day); * habitual diet characterized by absence of any food supplements and alternative medication, probiotics and prebiotics, whole grain and/or fiber enriched foods; * intake of fruit/vegetables \< 3 servings/day; * low level of physical activity (\< 500 metabolic equivalent min/week); * signed written informed consent. Exclusion Criteria: * food allergies and intolerances and celiac disease; * gastrointestinal diseases; * relevant diseases; * pregnant or breastfeeding; * previous abdominal surgery; * hypertriglyceridemia (Triglycerides \> 200 mg/dL); * hypercholesterolemia (Total cholesterol \> 200 mg/dL); * hyperglycaemia (glycaemia ≥ 110 mg/dL); * hypertension (arterial blood pressure ≥140/90 mm Hg); * weight loss ≥ 3 kg within 2 months before the study; * antibiotics treatment within 3 months before the study; * any medication (different from antibiotics) at the enrollment and within 2 months before the study; * habitual diet characterized by high fruit and vegetables intakes (\>3 portion/die); * high level of physical activity; * Alcohol consumption ≥ 3 alcohol units per day; * simultaneous participation in other trial.