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RECRUITING
NCT04962867
PHASE2

NCCH2006/MK010 Trial (FORTUNE Trial)

Sponsor: National Cancer Center, Japan

View on ClinicalTrials.gov

Summary

This is a single-arm, open-label, multicenter, investigator-initiated Phase 2 trial to evaluate the efficacy and safety of E7090 in patients with advanced or recurrent solid tumors harboring FGFR genetic alterations (including fusion, mutation, amplification).

Official title: Multicenter Investigator-initiated Phase II Trial of E7090 in Patients With Advanced or Recurrent Solid Tumor With Fibroblast Growth Factor Receptor (FGFR) Gene Alteration (FORTUNE Trial)

Key Details

Gender

All

Age Range

20 Years - Any

Study Type

INTERVENTIONAL

Enrollment

75

Start Date

2021-06-15

Completion Date

2028-03-31

Last Updated

2025-10-03

Healthy Volunteers

No

Interventions

DRUG

E7090

140 mg of E7090 is orally administered once daily.

Locations (7)

National Cancer Center Hospital

Chuo-ku, Tokyo, Japan, Japan

Kanagawa Cancer Center

Yokohama, Kanagawa, Japan

Tohoku University Hospital

Aoba-ku, Sendai, Miyagi, Japan

Kyushu University Hospital

Higashi-Ku, Fukuoka, Japan

Hokkaido University Hospital

Kita-Ku, Sapporo, Hokkaido, Japan

Okayama University Hospital

Okayama, Japan

Kyoto University Hospital

Sakyo-ku, Kyoto, Japan