Clinical Research Directory

Inclusion Criteria: * Women with moderate or severe intrauterine adhesions according to the AFS classification, i.e AFS score \>=5, confirmed by hysteroscopy right before adhesiolysis * Scheduled for hysteroscopic adhesiolysis * Age above or equal to 18 * Subjects who are willing to provide a written informed consent. * Subjects who can comply with the study follow-up (second look hysteroscopy) and other study requirements * Subjects who agree to refrain from intercourse or use a reliable form of barrier contraception to prevent unintended pregnancy until the follow-up hysteroscopy. * Subjects who agree to avoid all intrauterine devices (IUDs) until the follow-up hysteroscopy. Exclusion Criteria: Pre-operative criteria * Post menopause * Pregnant (confirmed by a positive pregnancy test) or lactating * Abnormal uterine cavity according to ESHRE classification I to V such as unicornis, bicornis, septate, duplex * Known or suspected endometrial hyperplasia * History of cervical or endometrial cancer * Active pelvic infection or history of pelvic peritonitis * History of endometrial ablation * Known contraindication or hypersensitivity to Womed Leaf component * Current participation in another clinical investigation that has not yet received the primary endpoint. * Any other condition that makes participation in the study contrary to the patient's best interests. Intra-operative criteria, post adhesiolysis: * Perforation during adhesiolysis * Uterine depth \< 5cm or \> 10cm