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Supplementation of n-3 PUFA in the Modulation of Lean Mass in Patients With Lung Cancer Receiving a High-protein Diet
Sponsor: Universidade Federal do Rio de Janeiro
Summary
This study is conducted to test the hypothesis that patients with lung cancer undergoing treatment with immunotherapy, chemotherapy and tyrosine Kinase Inhibitors receiving a high protein diet and supplemented with fish oil will improve muscle mass, therapeutic response and modulate the intestinal microbiota within a 4 month period.
Official title: Effect of Supplementation of Poly-unsaturated n-3 Fatty Acids and High-protein Diet on Epigenetic Modulation of Muscle Mass, Dose-limiting Toxicity and Intestinal Microbiota in Patients With Lung Cancer Submitted to Treatment With Immunotherapy, Chemotherapy and Tyrosine Kinase Inhibitors.
Key Details
Gender
All
Age Range
20 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2022-11-15
Completion Date
2025-03-15
Last Updated
2024-05-17
Healthy Volunteers
No
Conditions
Interventions
Placebo
Drug: Placebo olive oil pill manufactured to mimic fish oil. Other Names: • Placebo
Fish oil
All subjects will be given fish oil with a dose of of 2.100 mg of EPA and 924 mg of DHA, in four tablet twice daily for four mounths.
Locations (1)
Federal University of Rio de Janeiro
Rio de Janeiro, Rio de Janeiro, Brazil