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Myocardial Injury and Outcomes Following COVID-19 Vaccination (MYOVAX Study)
Sponsor: University Health Network, Toronto
Summary
The study will focus on cardiac blood and imaging biomarkers to facilitate early recognition of patients at risk for myocardial injury after COVID-19 vaccination. Ultimately, the intention is to identify patients at risk, reduce adverse events, and determine the need for longer-term follow-up in patients with myocardial injury after vaccination.
Key Details
Gender
All
Age Range
17 Years - Any
Study Type
INTERVENTIONAL
Enrollment
57
Start Date
2021-08-05
Completion Date
2026-08-05
Last Updated
2026-03-27
Healthy Volunteers
Yes
Interventions
Cardiac PET/MRI
An imaging technique that combines the strengths of both MRI and PET into one comprehensive study. This technique allows for detailed myocardial tissue characterization with MRI (including assessment of myocardial edema and fibrosis) and metabolic changes (including myocardial inflammation).
Blood Biomarkers
Markers of cardiac damage, inflammation, circulating microRNA profiles, and COVID antibody levels will be evaluated in patients after COVID-19 vaccination.
Locations (1)
University Health Network
Toronto, Ontario, Canada