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The Immune Responses After Hepatitis B Revaccination Doses in a Young Cohort
Sponsor: National Taiwan University Hospital
Summary
This prospective cohort study aims to provide the evidence-based clinical guide to help decide the revaccination doses of hepatitis B vaccine that the high-risk young adults without hepatitis B seroprotective antibodies (anti-HBs titer\<10 mIU/mL) need to take.
Key Details
Gender
All
Age Range
20 Years - 36 Years
Study Type
INTERVENTIONAL
Enrollment
240
Start Date
2021-08-01
Completion Date
2027-12-31
Last Updated
2025-03-20
Healthy Volunteers
Yes
Interventions
recombinant hepatitis B vaccine
Hepatitis B vaccine (Engerix-B) will be administered to the eligible participants by 4 groups. Each case will be tracked for 12 months, at 0, 7-10 days, 28 days, 24-28 weeks, 48-52 weeks anti-HBs titer concentration and 4 follow-up questionnaires.
Locations (1)
Family Medicine, NTUH
Taipei, Taiwan