Clinical Research Directory

Inclusion Criteria: * Informed consent as documented by signature. * Confirmed Parkinson's disease according to British brain bank criteria. * Hoehn and Yahr Stage 0 - 2.5 on medication. * Stable on PD treatment for a month at least. * Absence of dementia confirmed by cognitive testing (MoCA \>25). Exclusion Criteria: * Contraindications to the class of drugs under study, e.g., known hypersensitivity or allergy to class of drugs or the investigational product. * Women who are pregnant or breast feeding, or planning to become pregnant during the course of the trial or in the 3 months following the trial. * Lack of safe contraception in women with childbearing potential * Other clinically significant concomitant disease states (e.g., renal failure, hepatic dysfunction, cardiovascular disease, etc) that is not under stable control. * Subject has an atypical parkinsonian syndrome or secondary parkinsonism. * Patients with comorbidity that may interfere with the course of the trial.