Clinical Research Directory
Browse clinical research sites, groups, and studies.
Development of Effective, Opioid Sparing Techniques for Peri-operative Pain Management of Transgender Patients Undergoing Gender Affirming Surgeries
Sponsor: Cedars-Sinai Medical Center
Summary
This study will compare the current standard-of-care pain treatment regimen options that are available to patients who undergo gender-affirming surgery. The purpose of this research is to determine if any of these options are more (versus less) effective than the others to manage surgery related pain, after surgery.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
640
Start Date
2021-11-11
Completion Date
2026-09-30
Last Updated
2025-09-17
Healthy Volunteers
No
Conditions
Interventions
Ultrasound guided Continuous Infraclavicular Brachial Plexus Block
20cc of 0.25% bupivacaine + 1:200K epinephrine will be administered at start of case, 20cc of 0.25% bupivacaine + 1:200K epinephrine at end of case, and 6cc/hr of 0.25% bupivacaine at post-op \[administered by anesthesiologist\]
Ultrasound guided Continuous Femoral Nerve Block
20cc of 0.25% bupivacaine + 1:200K epinephrine will be administered at start of case, 20cc of 0.25% bupivacaine + 1:200K epinephrine at end of case, and 6cc/hr of 0.25% bupivacaine at post-op \[administered by anesthesiologist\]
Ultrasound guided Pudendal Nerve Block
20-40cc of 0.25% bupivacaine + 1:200K epinephrine \[administered by anesthesiologist, pre-incision\]
Bupivacaine
0.25% or 0.5% with or without 1:200K epinephrine
Bilateral ultrasound guided Transversus Abdominis Plane Block
40-60cc of 0.25% bupivacaine + 1:200K epinephrine \[administered by anesthesiologist post-op or at end of surgery\]
Bilateral spermatic cord block
10cc per spermatic cord of 0.5% bupivacaine \[administered by surgeon @ intraop\]
Pecs I & II Block
0.25% bupivacaine: 15-30mL per side for Pecs I-III
Local anesthetic
0.25% or 0.5% bupivacaine into the appropriate surgical site
Locations (1)
Cedars-Sinai Medical Center - North and South Towers
Los Angeles, California, United States