Clinical Research Directory

Inclusion Criteria: * Children aged 7-12 years * CPTS-RI total score ≥40 * Primary diagnosis of PTSD (6 months or more after the traumatic event) * Heart rate ≥ 55 bpm * Systolic blood pressure ≥ 95 mm Hg * Affiliation to a social security scheme * Written consent signed by the parents/holders of parental authority and the investigator * Acceptance of the protocol by the child-Child and Parents/Holders of parental authority fluent in French Exclusion Criteria: * Age\<7 years or ≥13 years * Children whose parents have been deprived of their authority * Contraindication to propranolol (cardiogenic shock, sinus bradycardia, hypotension (\< fifth percentile oscillometric or \<2SD) (Banker et al., 2016 - see APPENDIX 1), greater than first-degree heart block, heart failure, bronchial asthma and hypersensitivity to propranolol hydrochloride) * Concurrent medication with possible interactions with propranolol (cf 8.2) * Concurrent psychotropic drugs that have been shown to be effective in improving symptoms of PTSD (Antidepressants, atypical antipsychotics, mood stabilizers) * Concurrent psychotherapy (\>1 structured session/month declared by the clinician who follows the child) * Current active psychosis, anorexia nervosa, bulimia nervosa, binge-eating disorder, attention-deficit hyperactivity disorder, autism spectrum disorder * Children with psoriasis * Children with a predisposition to hypoglycemia * Obsessive-compulsive disorders * Bipolar Disorders * Mental retardation, * Traumatic brain injury (loss of consciousness \> 10 minutes) * Currently treated with a bradycardic drug * Concurrent participation to another interventional study * Renal or Hepatic Impairment * Pregnancy