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High-definition Surface Electromyography Markers for the Diagnosis of Sarcopenia
Sponsor: Assistance Publique - Hôpitaux de Paris
Summary
Sarcopenia is a progressive and generalised skeletal muscle disorder involving the accelerated loss of muscle mass and function that is associated with increased adverse outcomes including falls, functional decline, frailty, and mortality. In this pilot project, the investigators want to explore the potential of the high-definition surface electromyography technology (HD-sEMG) for the diagnosis of sarcopenia. This is a monocentric, descriptive, cross-sectional, parallel group study to develop a new diagnostic method. It is planned to include 50 people aged 75 years and over hospitalized in the acute geriatric ward and suspected of sarcopenia (Score ≥4 on the SARC-F screening questionnaire). The inclusion duration will be 36 months and adding a 1-month patient follow-up as part of routine care, the total study duration will be 37 months. Patients will have their body composition (muscle mass, fat mass, and bone mass) using dual X-ray absorptiometry (DEXA). Muscular strength will be assessed by handgrip strength. Physical performance will be assessed. Additional data will be collected from their medical records.
Official title: HD-sEMG Markers of Sarcopenia
Key Details
Gender
All
Age Range
75 Years - Any
Study Type
INTERVENTIONAL
Enrollment
175
Start Date
2022-05-18
Completion Date
2026-12-18
Last Updated
2025-05-23
Healthy Volunteers
Yes
Conditions
Interventions
HD-sEMG
high definition surface electromyography, allowing the recording of muscle activation signals sensitive to the intensity of the contraction and indirectly to the muscle strength as well as to the muscular fatigability, but also capable of measuring the modifications of the recruitment modalities of the motor units. This recording will be made on the rectus femoris during knee extension, either in the lying position or during chair lifts, depending on the patient's functional state.
- Quadriceps muscle ultrasound
Muscle Ultrasound with Philips Lumify Wireless Handheld Ultrasound for Android - Model - L12-4 linear probe, allowing performance at the patient's bed.
IPAQ Physical Activity Questionnaire.
physical activity assessment questionnaire/adapted version for seniors
Locations (6)
Service de gériatrie aigue polyvalente (GAP)
Ivry-sur-Seine, France
Service de soins de suite et de réadaptation Gériatrique 1
Ivry-sur-Seine, France
Service de soins de suite et de réadaptation gériatrique 2
Ivry-sur-Seine, France
Unité d'Explorations fonctionnelles du sujet âgé, Hôpital Charles Foix
Ivry-sur-Seine, France
Service de soins de suite et de réadaptation -Plaies et cicatrisation
Paris, France
Service de soins de suite et de réadaptation Gériatrique Hôpital Rothschild
Paris, France