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RECRUITING
NCT04990024
NA

The Effect of Different Diets on Arterial Stiffness in Obese Patients on Semaglutide

Sponsor: American University of Beirut Medical Center

View on ClinicalTrials.gov

Summary

In patients initiating Semaglutide for weight management, the objective is to compare the effect of the Mediterranean diet and the high protein/low carbohydrate (HP/LC) diet CV parameters, namely arterial stiffness, measured by carotid-femoral pulse wave velocity (cfPWV), and visceral adipose tissue, in addition to other metabolic indicators.

Official title: The Effect of Mediterranean or High Protein/Low Carbohydrate Diet on Arterial Stiffness in Non-diabetic, Obese Patients on Semaglutide: A Randomized Controlled Trial

Key Details

Gender

All

Age Range

18 Years - 49 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2021-07-01

Completion Date

2025-09-15

Last Updated

2024-08-06

Healthy Volunteers

Yes

Interventions

OTHER

Dietary Intervention Med Diet

The diet will consist of a calorie-restricted Med diet, with 500 Kcal/d energy restriction. The intervention consists of individual and reinforcement sessions on Med diet. During these sessions, the RA will go over the benefits of Med diet, what composition it should have, and how to make appropriate choices for meal planning, in addition to providing food lists, by season. The individual sessions with subjects will also allow to individualize the diet plan.

OTHER

Dietary Intervention HP/LC Diet

This is a non-ketogenic diet consisting of ad libitum intake of proteins, fat, and vegetables, with restriction of daily carbohydrates to \<130 g/d. The intervention consists of individual and reinforcement educational sessions on HP/LC, same as with Med diet (above). The individual sessions with subjects will also allow to individualize the diet plan.

Locations (1)

American University of Beirut - Medical Center

Beirut, Riad El Solh, Lebanon