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RECRUITING
NCT04993859

Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children

Sponsor: University of Colorado, Denver

View on ClinicalTrials.gov

Summary

The over-arching aim of this study is to evaluate the effects of two specific anti-cancer chemotherapies, vincristine and doxorubicin, on bladder function and urine composition.

Key Details

Gender

All

Age Range

5 Years - 13 Years

Study Type

OBSERVATIONAL

Enrollment

152

Start Date

2021-06-02

Completion Date

2026-07-09

Last Updated

2025-10-15

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Non-invasive Urodynamic Test (niUDS)

A noninvasive urodynamics is a simple test used to evaluate urinary flow.

DIAGNOSTIC_TEST

Urinary proteomic screen

Urine proteomics is a powerful platform to identify urinary excreted proteins and peptides in different stages of disease or therapy and to determine their quantity, functions, and interaction.

OTHER

Dysfunctional Voiding Symptom Score Survey (DVSS)

The Dysfunctional Voiding Symptom Score provides accurate and objective grading of voiding behaviors of children.

Locations (1)

Children's Hospital Colorado

Aurora, Colorado, United States