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ENROLLING BY INVITATION
NCT04996706

Evaluation of Lymphoma Prognosis and Survivorship in Recently Diagnosed Patients, LEO Study

Sponsor: Mayo Clinic

View on ClinicalTrials.gov

Summary

The goal of this infrastructure protocol is to build and maintain a large and diverse observational cohort study to support broad and cutting-edge research focused on NHL prognosis and survivorship. The LEO cohort will promote identification of clinical (including co-morbid diseases), epidemiologic (including lifestyle and other exposures), host genetic, tumor, and treatment factors that impact multiple outcomes (including event-free, overall and lymphoma-specific survival; new onset comorbidities; and patient-reported outcomes). This resource also will allow examination of the interaction among these factors in order to better understand the clinical and molecular epidemiology of outcomes in NHL. Ultimately, this approach will drive discovery and validation of treatment endpoints, improve prognostication, and identify novel approaches to improve short and long-term outcomes for NHL patients.

Official title: The Lymphoma Epidemiology of Outcomes (LEO) Cohort Study Protocol

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

21000

Start Date

2021-08-16

Completion Date

2031-03-31

Last Updated

2026-02-27

Healthy Volunteers

Not specified

Locations (10)

Mayo Clinic in Arizona

Scottsdale, Arizona, United States

Mayo Clinic in Florida

Jacksonville, Florida, United States

University of Miami: Sylvester Comprehensive Cancer Center

Miami, Florida, United States

Winship Cancer Institute of Emory University

Atlanta, Georgia, United States

University of Iowa

Iowa City, Iowa, United States

Mayo Clinic

Rochester, Minnesota, United States

Washington University School of Medicine in St. Louis

St Louis, Missouri, United States

Weill Cornell Medical College

New York, New York, United States

University of Rochester Medical Center

Rochester, New York, United States

MD Anderson Cancer Center

Houston, Texas, United States