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Evaluation of Lymphoma Prognosis and Survivorship in Recently Diagnosed Patients, LEO Study
Sponsor: Mayo Clinic
Summary
The goal of this infrastructure protocol is to build and maintain a large and diverse observational cohort study to support broad and cutting-edge research focused on NHL prognosis and survivorship. The LEO cohort will promote identification of clinical (including co-morbid diseases), epidemiologic (including lifestyle and other exposures), host genetic, tumor, and treatment factors that impact multiple outcomes (including event-free, overall and lymphoma-specific survival; new onset comorbidities; and patient-reported outcomes). This resource also will allow examination of the interaction among these factors in order to better understand the clinical and molecular epidemiology of outcomes in NHL. Ultimately, this approach will drive discovery and validation of treatment endpoints, improve prognostication, and identify novel approaches to improve short and long-term outcomes for NHL patients.
Official title: The Lymphoma Epidemiology of Outcomes (LEO) Cohort Study Protocol
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
21000
Start Date
2021-08-16
Completion Date
2031-03-31
Last Updated
2026-02-27
Healthy Volunteers
Not specified
Conditions
Locations (10)
Mayo Clinic in Arizona
Scottsdale, Arizona, United States
Mayo Clinic in Florida
Jacksonville, Florida, United States
University of Miami: Sylvester Comprehensive Cancer Center
Miami, Florida, United States
Winship Cancer Institute of Emory University
Atlanta, Georgia, United States
University of Iowa
Iowa City, Iowa, United States
Mayo Clinic
Rochester, Minnesota, United States
Washington University School of Medicine in St. Louis
St Louis, Missouri, United States
Weill Cornell Medical College
New York, New York, United States
University of Rochester Medical Center
Rochester, New York, United States
MD Anderson Cancer Center
Houston, Texas, United States