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Cardiovascular Injury and Cardiac Fitness in Locally Advanced Non-Small Cell Lung Cancer Patients Receiving Model Based Personalized Chemoradiation
Sponsor: M.D. Anderson Cancer Center
Summary
This study assesses cardiovascular injury and cardiac fitness in patients with non-small cell lung cancer that has spread to nearby tissue or lymph nodes (locally advanced) receiving model based personalized chemoradiation. The goal of this study is to learn more about the risk of developing heart disease as a result of chemoradiation treatment for lung cancer. Researchers also want to learn if the risk can be reduced by using a patient's individual risk profile to guide cancer treatment and help protect the heart.
Official title: Longitudinal Assessment of Cardiovascular Injury and Cardiac Fitness in LA-NSCLC Patients Receiving Model Based Personalized Chemoradiation - an Adaptive Cohort Registration Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2021-07-05
Completion Date
2027-02-02
Last Updated
2026-03-11
Healthy Volunteers
No
Conditions
Interventions
6 Minute Walk Functional Test
Participate in 6 MWT
Biospecimen Collection
Undergo blood and urine sample collection
Computed Tomography
Undergo SPECT/CT
Echocardiography
Undergo echocardiogram
Exercise Cardiac Stress Test
Undergo stress test
Questionnaire Administration
Complete questionnaires
Single Photon Emission Computed Tomography
Undergo SPECT/CT
Locations (1)
M D Anderson Cancer Center
Houston, Texas, United States