Clinical Research Directory

Insulin Sensitivity After Breast Cancer

Sponsor: University of Copenhagen

Summary

Epidemiological studies have revealed that 60-80% of women with breast cancer (BC) develop metabolic disorders that are similar to those observed in conditions like type 2 diabetes. These metabolic disorders, including insulin resistance, obesity, hyperinsulinemia, and glucose intolerance, are associated with increased BC recurrence and mortality. Skeletal muscle is the major site of glucose uptake in humans. The aims of the present project are to 1) determine the involvement of insulin resistance in skeletal muscle in the metabolic disorders prevalent in BC survivors, 2) identify BC-and/or treatment-induced molecular changes in skeletal muscle from BC survivors .

Official title: Study of Molecular Causes of Metabolic Disorders in Obese Premenopausal Women After Breast Cancer

Key Details

Conditions

Interventions

Locations (1)