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GOLD 0 - DLCO 1: A Look Beyond the Obstruction. Is Spirometry Enough for COPD (Chronic Obstructive Pulmonary Disease) Screening?
Sponsor: Fundación para la Investigación del Hospital Clínico de Valencia
Summary
This is a multicenter observational prospective study in smokers or ex-smokers with cumulative exposure ≥ 10 a / p (years / pack) with respiratory symptoms and presenting a normal spirometry. The patients who sign the corresponding informed consent, will undergo a DLCO and will be divided into two groups according to the result: * Group I. Patients with DLCO \<80%. * Group II Patients with DLCO≥80%. Both groups will be followed for 5 years.
Official title: GOLD 0 - DLCO 1: A Look Beyond the Obstruction. Is Spirometry Enough for COPD Screening?
Key Details
Gender
All
Age Range
18 Years - 99 Years
Study Type
OBSERVATIONAL
Enrollment
236
Start Date
2021-09-10
Completion Date
2025-12-31
Last Updated
2026-09-04
Healthy Volunteers
No
Interventions
Standard Care
Patients will followed during 5 years, and only 2 visits , baseline and 5 years
Standard Care plus oxidative stress study plus inflammation biomarkers study
Patients will followed during 5 years, Annual follo-up visits will be carried out during this period
Locations (1)
Hospital Clínico Universitario de Valencia
Valencia, Valencia, Spain