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RECRUITING
NCT05020574
PHASE2

Microbiome and Association With Implant Infections

Sponsor: University of California, San Francisco

View on ClinicalTrials.gov

Summary

The most common tissue expander-related infections are from Staphylococcus and Pseudomonas species. In addition, from breast tissue microbiome studies, Staphylococcus and Pseudomonas show variable abundance across samples. The investigator hypothesizes that participants undergoing mastectomy with high initial abundance of Staphylococcus and/or Pseudomonas are more likely to develop subsequent tissue expander-related infections from these respective organisms.

Official title: Microbiome and Association With Implant Infections: Investigating the Impact of Antibiotics on the Gut and Breast Microbiomes Post-mastectomy With Implant-based Breast Reconstruction

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

200

Start Date

2021-09-28

Completion Date

2026-12-31

Last Updated

2026-03-18

Healthy Volunteers

No

Interventions

DRUG

Cephalexin

Given orally (PO)

Locations (1)

University of California, San Francisco

San Francisco, California, United States