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Microbiome and Association With Implant Infections
Sponsor: University of California, San Francisco
Summary
The most common tissue expander-related infections are from Staphylococcus and Pseudomonas species. In addition, from breast tissue microbiome studies, Staphylococcus and Pseudomonas show variable abundance across samples. The investigator hypothesizes that participants undergoing mastectomy with high initial abundance of Staphylococcus and/or Pseudomonas are more likely to develop subsequent tissue expander-related infections from these respective organisms.
Official title: Microbiome and Association With Implant Infections: Investigating the Impact of Antibiotics on the Gut and Breast Microbiomes Post-mastectomy With Implant-based Breast Reconstruction
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2021-09-28
Completion Date
2026-12-31
Last Updated
2026-03-18
Healthy Volunteers
No
Interventions
Cephalexin
Given orally (PO)
Locations (1)
University of California, San Francisco
San Francisco, California, United States