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Alteration of the Immune Microenvironment in Basal Cell Carcinoma Following Photodynamic Therapy
Sponsor: Case Comprehensive Cancer Center
Summary
The purpose of this study is to better understand the immune response to basal cell carcinoma (BCC) treated with Photodynamic Therapy (PDT) in order to develop new methods of treating BCC. Previous research suggests that PDT alters the immune response, possibly in a way that could promote better tumor clearance when combined with other treatments. Overall, participation in this study will help the study team better understand the anti-tumor immune response when BCC is treated with PDT.
Official title: Alteration of the Immune Microenvironment in Basal Cell Carcinoma (BCC) Following Photodynamic Therapy (PDT)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
28
Start Date
2021-12-13
Completion Date
2027-12
Last Updated
2025-11-26
Healthy Volunteers
No
Conditions
Interventions
ALA
At first visit, ALA applied to one BCC lesion
PDT
PDT with blue light (for 30 min (\~20 mJ/cm2))
Locations (1)
Cleveland Clinic, Case Comprehensive Cancer Center
Cleveland, Ohio, United States