Clinical Research Directory

Inclusion Criteria: * Meet the diagnostic criteria for immune thrombocytopenia; * Untreated hospitalized patients or patients from the clinic, may be male or female, between the ages of 18\~ 80 years; * To show a platelet count \<30 \* 10\^9/L, or with bleeding manifestations, or both; * Willing and able to sign written informed consent * ITP patients with hepatitis virus infection or ITP patients with abnormal liver function at the time of enrollment, i.e., ITP patients with indications for diammonium glycyrrhizinate enteric-coated capsule, should be separately stratified. Exclusion Criteria: * secondary thrombocytopenia; * severe immune-deficiency; * active or previous malignancy; * HIV virus infection, tuberculosis, or other active infection (sepsis, pneumonia, or abscess); * pregnancy or lactation; * diabetes; * hypertension; * cardiovascular diseases; * severe kidney function impairment; * psychosis; * osteoporosis; * inflammatory bowel disease or gastric disease; * arterial or venous thromboembolism within the 6 months before screening or patients who required anticoagulant treatment; * an organ or haematopoietic stem-cell transplantation; * neutrophil count of less than 1500 cells per mm³; * glycosylated haemoglobin less than 8%; * partial thromboplastin time 1∙5 times or less the upper limit of normal (ULN); •clinical electrocardiogram changes; * history of primary immunodeficiency; * neoplastic disease within the past 5 years; * corrected QT interval greater than 450 ms for men and greater than 470 ms for women; * substance misuse within the previous 12 months; * people who could not adhere to the protocol or were planning to have a surgical procedure in 6 months.