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Testosterone Levels and Cutibacterium
Sponsor: University of Washington
Summary
Phase 1: In 51 patients undergoing shoulder arthroplasties, total serum testosterone, free testosterone and sex hormone binding globulin levels obtained in the clinic before surgery were correlated with the levels of Cutibacterium on the skin in clinic, in the operating room prior to surgery, and in the skin incision. Phase 2: The investigators wish to determine if preoperative serum testosterone levels are associated with risk for shoulder PJI (periprosthetic joint infection) in patients undergoing primary shoulder arthroplasty. Also to determine if preoperative serum testosterone levels are predictive of bacterial load of deep tissue cultures taken at the time of revision shoulder arthroplasty in patients undergoing primary shoulder arthroplasty.
Official title: Association Between Serum Testosterone Levels and Cutibacterium Culture Positivity During Shoulder Arthroplasty
Key Details
Gender
All
Age Range
18 Years - 89 Years
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2020-07-01
Completion Date
2027-01-01
Last Updated
2025-03-30
Healthy Volunteers
No
Conditions
Locations (1)
University of Washington
Seattle, Washington, United States