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A Study to Evaluate the Efficacy and Safety of CYH33 in Patients With Recurrent/Persistent Ovary Clear Cell Carcinoma
Sponsor: Haihe Biopharma Co., Ltd.
Summary
The purpose of this study is to determine the treatment efficacy of CYH33 monotherapy in patients with recurrent or persistent ovarian, fallopian tube or primary peritoneal clear cell carcinoma harboring PIK3CA hotspot mutation, who received prior systemic anti-tumor treatment.
Official title: A Phase II, Open-Label, Multicenter Study to Evaluate the Efficacy and Safety of CYH33, a Selective PI3Kα Inhibitor in Patients With Recurrent/Persistent Ovary, Fallopian Tube or Primary Peritoneal Clear Cell Carcinoma
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
93
Start Date
2021-10-11
Completion Date
2026-02-28
Last Updated
2026-01-30
Healthy Volunteers
No
Conditions
Interventions
CYH33
a Selective PI3Kα Inhibitor
Locations (36)
Beijing Obstetrics and Gynecology Hospital, Capital Medical University
Beijing, China
Chinese PLA General Hospital
Beijing, China
The First Affiliated Hospital of Chongqing Medical University
Chongqing, China
The Southwest Hospital of AMU
Chongqing, China
Sun Yat-sen University Cancer Center
Guangdong, China
The First Affiliated Hospital, Sun Yat-sen University
Guangdong, China
The First Affiliated Hospital of Hainan Medical College
Haikou, China
The Third People's Hospital of Hainan Province
Hainan, China
The First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, China
Zhejiang Cancer Hospital
Hangzhou, China
Harbin Medical University Cancer Hospital
Harbin, China
Hubei Cancer Hospital
Hubei, China
Hunan Cancer Hospital
Hunan, China
Qilu Hospital of Shandong University
Jinan, China
Jiangsu Province Hospital
Nanjing, China
The People's Hospital Of Guangxi Zhuang Autonomous Region
Nanning, China
Qingdao Central Hospital
Qingdao, China
Obstetrics & Gynecology Hospital of Fudan University
Shanghai, China
Shanghai First Maternity and Infant Hospital
Shanghai, China
Xiaohua wu
Shanghai, China
West China Second University Hospital, Sichuan University
Sichuan, China
Tianjin Medical University General Hospital
Tianjin, China
Zhongnan Hospital of Wuhan University
Wuhan, China
The First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, China
Sir Run Run Shaw Hospital， School of Medicine, Zhejiang University
Zhejiang, China
Kurume University Hospital
Kurume, Fukuoka, Japan
Osaka University Hospital
Suita, Osaka, Japan
National Cancer Center Hospital
Chuo Ku, Tokyo, Japan
Jikei University Hospital
Minato-Ku, Tokyo, Japan
Keio University Hospital
Shinjuku-Ku, Tokyo, Japan
Shikoku Cancer Center
Matsuyama, Japan
Nagoya University Hospital
Nagoya, Japan
Niigata University Medical & Dental Hospital
Niigata, Japan
Okayama University Hospital
Okayama, Japan
Hokkaido University Hospital
Sapporo, Japan
Tohoku University Hospital
Sendai, Japan