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RECRUITING
NCT05045066
EARLY_PHASE1

Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients

Sponsor: Mayo Clinic

View on ClinicalTrials.gov

Summary

This early phase I is to find out how common vitamin D insufficiency is among African American patients with a history of prostate cancer that has not spread to other parts of the body (localized) or has spread to other places in the body (metastatic) and how vitamin D insufficiency affects the immune system. This study also aims to find out if replacing vitamin D results in normalization of the immune function. Information from this study may benefit prostate cancer patients by identifying vitamin D insufficiency which in several studies had been found to contribute to more aggressive prostate cancers.

Official title: MC210501 Differences in Immunological Effects of Vitamin D Replacement Among Black/ African American (AA) Prostate Cancer Patients With Localized Versus Metastatic Disease

Key Details

Gender

MALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

220

Start Date

2021-12-29

Completion Date

2029-08-31

Last Updated

2026-03-02

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

Cholecalciferol

Given PO

OTHER

Quality-of-Life Assessment

Ancillary studies

PROCEDURE

Biospecimen Collection

Undergo blood sample collection

Locations (2)

Mayo Clinic in Arizona

Scottsdale, Arizona, United States

Mayo Clinic in Florida

Jacksonville, Florida, United States