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ACTIVE NOT RECRUITING
NCT05045391

Pulmonary Aspergillosis in Tuberculosis Patients

Sponsor: Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan

View on ClinicalTrials.gov

Summary

Pulmonary tuberculosis (PTB) is the most common cause of lung destruction, contributing to coinfections development, and Aspergillosis spp. is one of the most important. Diagnosis of chronic pulmonary aspergillosis (CPA) in PTB patients is difficult due to similarity of clinical and radiological data, especially in resource-constrained settings. Differentiation of PTB patients with singling out a group with a higher Aspergillus IgG level during the initial examination will help physicians to orient to further examination of CPA. Objectives: to determine the prevalence of aspergillosis in Koch's bacillus-positive and Koch's bacillus-negative PTB patients and antifungal resistance of Aspergillus species isolates in Central Asia countries.

Official title: Prevalence of Chronic Pulmonary Aspergillosis and Antifungal Drug Resistance of Aspergillus Spp. in Pulmonary Tuberculosis Patients in Uzbekistan

Key Details

Gender

All

Age Range

19 Years - 90 Years

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2020-01-01

Completion Date

2030-12-31

Last Updated

2025-04-04

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Aspergillus IgG detection

Aspergillus IgG will be detected among pulmonary tuberculosis patients. 5 ml of vein blood will be collected for ELISA.

Locations (1)

Research institute of epidemiology, microbiology and infectious diseases

Tashkent, Uchtepa, Uzbekistan